A diving accident in 1967 left Tada hospitalized and paralyzed (as a quadriplegic; unable to use her hands or legs.) After two years of rehabilitation and in a wheelchair, Tada began working to help others in similar situations.
Tada wrote of her experiences in her international best-selling autobiography, Joni, which has been distributed in many languages, and which was made into a feature film of the same name.
Tada founded Joni and Friends (JAF) in 1979, an organization for Christian ministry in the disability community throughout the world. The organization grew into the establishment in 2006 of the Joni and Friends International Disability Center (IDC).